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Recent Additions: New and Updated Entries in the Past 60 Days
Displaying entries 76 through 82 of 82 found.


Earth Earns: An Open Participatory Earthropocene to Astropocene CoCreative Future

Ecosmo Sapiens > New Earth > second genesis

Mu, Wenjing, et al. Superstructural ordering in self-sorting coacervate-based protocell networks. Nature Chemistry. February, 2024. Chinese Academy of Sciences, Beijing, Beijing University of Chemical Technology, and Centre for Protolife Research School of Chemistry, University of Bristol (Stephen Mann) researchers post initial array of approaches and techniques by which various synthetic organisms may be brought into being. But at this early stage of intentional procreation, any foray as this must have serious ethical, philosophic and commom guidance before going further.


Bottom-up assembly of higher-order cyto-mimetic systems capable of coordinated physical behaviours, collective chemical signalling and spatially integrated processing is a pathway toward an artificial multicellularity. Here we develop coacervate microdroplets that self-sort into protocell networks. The protocell superstructures exhibit macromolecular spatial enzyme/ribozyme biocatalysis and molecular translocation. These methodologies are a step towards the spontaneous orchestration of protocell models into artificial tissues and colonies with ordered architectures and collective functions. (Abstract)

Ecosmo Sapiens > New Earth > second genesis

Noshay, JaclEleven computational biologists at Oak Ridge Nayn, et al. Quantum biological insights into CRISPR-Cas9 sgRNA efficiency from explainable-AI driven feature engineering. Nucleic Acids Research. 51/19, 2023. Eleven computational biologists at Oak Ridge National Laboratory and the University of Tennessee explain a novel synthesis of these genetic editing abilities with quantum physical (organic) principles.

CRISPR-Cas9 tools have transformed genetic manipulation capabilities. While empirical rules have been developed for a range of model organisms, the basis for sgRNA efficiency remains poorly understood. Here we enter a novel feature set and a new public resource by way of quantum chemical tensors. We use the iterative AI model known as Random Forest (iRF) to encode attributes of position-specific sequences for Escherichia coli sgRNAs and identify traits for sgRNA design in bacterial species. We believe that these encodings can enhance our understanding of the quantum biological processes involved in the CRISPR-Cas9 machinery. (Abstract)

Ecosmo Sapiens > New Earth > second genesis

Velasco-Garcia, Laura and Carla Casadevall. Bioinspired photocatalytic systems towards compartmentalized artificial photosynthesis. Communications Chemistry. 6/263, 2023. Institute of Chemical Research of Catalonia (ICIQ), Barcelona Institute of Science and Technology describe initial proof of principle verifications that these nature-based approaches can facilitate viable ways to achieve this vital biological process going forward.

Artificial photosynthesis aims to produce fuels and chemicals from simpler versions using sunlight as an energy source. To achieve novel photocatalysis, this review turns to bioinspired artificial vesicles as a source. We discuss recent examples such as light harvesting, charge transfer, and fuel production. These studies cite the pivotal role of the membrane to increase the stability of reaction partners, a suitable local environment, and force proximity between electron donor and acceptor molecules. Overall, these findings pave the way for further bioinspired artificial photosynthesis projects. (Excerpt)

Ecosmo Sapiens > New Earth > second genesis

Wytock, Thomas and Adison Motter. Cell reprogramming design by transfer learning of functional transcriptional networks. PNAS. 121/11, 2024. Northwestern University biophysicists (search AM) advance the latest mathematical insights into 3D genomics so to achieve better malady management and medicines.

The lack of genome-wide models for gene regulatory networks complicates the application of control theory to cell behavior. We address this by a transfer learning approach that leverages genome-wide transcriptomic profiles to characterize cell type attractors responses. These responses predict a combinatorial perturbation that minimizes the transcriptional difference between an initial and target cell type, bringing the regulatory network to the basin of attraction. This approach will enable the rapid identification of treatments for complex diseases, and how the dynamics of gene regulatory networks affect phenotypes. (Significance)

Ecosmo Sapiens > New Earth > democracy

McManus, Matthew. Liberal Socialism Now. Aeon Magazine. February, 2024. A University of Michigan political scientist posts a popular review of his thought and writings which have come to advocate an egalitarian reciprocity of personal and communal welfare. He notes how these polar options which have jostled each other through history are often misunderstood and ill defined. In our hyper-stressed moment it is imperative that an obvious middle way complementarity be considered.

The idea of ‘liberal socialism’ might appear odd and opposite. This would be true for those on the Right and the Left who regard liberalism as market capitalism. We must now make an effort to retrieve its historic theory and make the case for a new salience in the 21st century (see also my forthcoming book The Political Theory of Liberal Socialism). The composite phrase is a political ideology that combines support for many liberal institutions and rights with a socialist desire to establish far more equitable and democratic economic arrangements.

Nevertheless, all liberal socialists are committed to three central principles. First, they value (both) collectivism and normative individualism and believe that the wellbeing and free development of individual persons is a moral priority along with their embeddedness in society. Secondly, liberal socialists are committed to each person having an equal opportunity to lead a good life through the provision of shared resources. Third, they are committed to a basic social structure by participatory democratic policies and principles for family and the economy.

Ecosmo Sapiens > New Earth > democracy

Mulya, Didi Ahmad and Romi Muslim. Phase transition and universality of the majority-rule model on complex networks. arXiv:2402.13434. In a paper to appear in the International Journal of Modern Physics C, National Research and Innovation Agency, Indonesia, and University of Technology, Yogyakarta, Indonesia consider possible ways that bipolar political elections might be based in and attributed to basic statistical physics phenomena.

We investigate the phenomena of order-disorder phase transition and the universality of the majority rule model defined on three complex networks, namely the Barabasi-Albert, Watts-Strogatz, and Erdos-Renyi versions. Assume each agent holds two possible opinions distribute across the nodes. Based on our scaling analysis, it is found that the model undergoes a continuous phase transition, with critical points for independence model greater than the anticonformity model. We obtain critical exponents indicating that they exhibit the same universality class as the mean-field Ising model. (Abstract)

We conducted an analysis of the order-disorder phase transition and the universality class of the majority-rule model implemented on heterogeneous networks, wherein each node maintains connections to at least two other nodes. Each agent has two possible opinions across all network nodes. Each agent adheres to the principle of conformity by behavior aligned with the majority opinion. Notably, agents also exhibit anticonformity and independence proclivities. Within this model, anticonformist agents adopt the minority opinion, adjusting their opinion or state to align with the minority viewpoint, while independent agents act autonomously, unaffected by the influence of other agents. (5)

Ecosmo Sapiens > Viable Gaia

fisher, Len, et al. Sustainability: We need to focus on overall system outcomes rather than simplistic targets.. People and Nature. January, 2024. Veteran environmental theorists LF, University of Bristol, Thilo Gross, Helmholtz Institute for Functional Marine Biodiversity, Helmut Hillebrand, Ossietzky University, Germany; Anders Sandberg, Helmholtz Center for Marine and Polar Science, and Hiroki Sayama, SUNY Binghamton University scope out both the need to view and treat glocal Earth systems as an animate multiplex whole along with seeking working solutions guided the latest complexity realities.

Many of the global challenges that confront humanity are interlinked in a dynamic complex network, with multiple feedback loops, nonlinear interactions and interdependencies. In regard, an issue is that complex systems such as those formed by the network of global threats have emergent properties which are more than the sum of their parts. We must learn how to deal with or live with these properties if we are to find effective ways to cope with the threats, individually and collectively. Here, we argue that advances in complex systems research have enhanced our ability to analyse and model such entwined systems to the extent to offer a new approach to sustainability. (Excerpt)

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